Proteomics
ADAPTED: Identifying new medicines to treat Alzheimer’s Disease through greater understanding of the APOE gene.

The ADAPTED (Alzheimer’s Disease Apolipoprotein Pathology for Treatment Elucidation and Development)  project was a major new initiative to investigate an area of Alzheimer’s Disease (AD) research that has previously received little attention. The project aimed to improve understanding of the function of the APOE gene. APOE is well known as a risk factor for developing […]

News
New Focus, New Offerings: A more dynamic and diverse proteomic service

Latest News from DC Biosciences: The team at DC Biosciences is excited about bringing new ideas and an improved focus as the world moves forward to an easier and more productive time. Our aim is to provide a more dynamic and diverse proteomic service enabling us to provide the best match for your unique research […]

Proteomics
De Novo Protein Sequencing Technology

Our commitment to pursue the most pioneering, leading-edge proteomic technologies has driven us to add de novo Protein and Antibody Sequencing to our service provision. “This year we will focus on ensuring a seamless results-driven service and apply our extensive knowledge and experience across a broad range of pioneering proteomic disciplines to provide our customers with […]

Proteomics
Proteomics: A Timeline

Proteomics is the analysis of the entire protein complement of a cell, tissue, organism, or species. The application of technologies to identify and quantify proteins is crucial in early disease diagnosis, prognosis, and drug development. Proteomics as a discipline has its roots in the late 1800s with the emergence of rudimentary mass spectrometry. The following […]

News
What can proteomics contribute to COVID-19 research?

The COVID-19 pandemic is a global, public health crisis with far-reaching and long-term repercussions on the financial, physical, and psychological well-being of the population. As a consequence of the highly contagious nature of the disease, the virus has spread rapidly across the world. The disease is associated with severe pneumonia that often leads to acute […]

Jan Hewitt
Proteomics
Our Story – From formation to specialisation in proteomics

Hi, I’m Jan and I’m new around here. In fact, I’m new science altogether, but I am definitely learning new things every day and enjoying being a part of such a dynamic community. I wanted to learn a bit more about the history of DC Biosciences, how it became so pioneering in the field of […]

Jan Hewitt
Proteomics
EASI-tag, and why it is really exciting

There was an interesting paper recently:     A new type of Isobaric Labelling reagents? Do we really need more? Isn’t this what TMT and iTRAQ already do? Why is this important?   Isobaric Labelling In Isobaric Labelling, each sample is modified with different versions of a chemical label which are near identical but have […]

Dr. Armel Nicolas
News
When will you Click?

Click chemistry reactions are reactions between an alkyne-tagged molecule and an azide-tagged molecule which use copper as a catalyst. This was introduced by K. B. Sharpless in 2001 for which he was awarded half of the 2001 Nobel Prize in Chemistry. Sharpless developed these reactions in The Scripps Institute, California and has continued developing more […]

Shona Patton
Proteomics
Where to draw the line? Hypothesis Testing in Proteomics

So, you’ve got this beautiful proteomics experiment done. You just got your data (yay!), let’s say ratios of treated vs control, 3 replicates, simple experiment. But that’s thousands of protein groups, most of which are probably not interesting at all. We want to find out which proteins are regulated. How do we do it?   […]

Dr. Armel Nicolas
Proteomics
ADAPTED Project meeting in Edinburgh – understanding APOE

This week Francesco Rao attended a progress meeting for the ADAPTED project. For this meet up the city of choice was Edinburgh, some might argue the most beautiful city in the world! After a successful launch year, this was the first consortium meeting in 2018. With someone in the world developing Dementia every 3 seconds, the […]

Sarah Macdonald
Point of View