Click chemistry reactions are reactions between an alkyne-tagged molecule and an azide-tagged molecule which use copper as a catalyst. This was introduced by K. B. Sharpless in 2001 for which he was awarded half of the 2001 Nobel Prize in Chemistry. Sharpless developed these reactions in The Scripps Institute, California and has continued developing more reactions since.
The ultimate goal of click chemistry reactions is to work reliably in small and large scale applications. For a reaction to be defined as a click chemistry reaction it must be modular, efficient, and generate only by-products that can be easily removed. Most reactions are also very simple and use readily available reagents.
So, what exactly can click chemistry be used for?
The applications for using click chemistry is rapidly expanding any many areas, most of all drug discovery. The applications are endless:
What does this mean for you?
We supply a wide variety of click chemistry reagents, suitable for every application, including azide compounds, alkyne compounds, agarose resins, fluorescent labels and many more.
All of our products can be found here
We are happy to give guidance on what products would best suit your research.
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Data Dependent Acquisition (DDA) is the standard method for running LC-MS/MS experiments. Here, we present a quick overview of the DDA method, as well as of the less common Data Independent methods (DIA). In LC-MS/MS, purified peptides are separated on an online chromatography gradient (usually low pH Reverse Phase) over 1 to 4h and progressively […]
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Click chemistry reactions are reactions between an alkyne-tagged molecule and an azide-tagged molecule which use copper as a catalyst. This was introduced by K. B. Sharpless in 2001 for which he was awarded half of the 2001 Nobel Prize in Chemistry. Sharpless developed these reactions in The Scripps Institute, California and has continued developing more […]
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