An azide-activated, water-soluble Cy5.5 dye.
The NIR-fluorescent Cy5.5 azide can be reacted with terminal alkynes via a copper-catalysed click reaction (CuAAC). It also reacts with strained cyclo-octyne via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures. Cy5.5 is a water-soluble, pH-insensitive, bright fluorescent probe that can be used in place of Alexa Fluor® 680, DyLigh®t 680, or IRDye™ 680 and other dyes excitable at a wavelength at around 680nm.
This sulfonated dye is also known as sulfo-Cyanine5.5 Azide. Cy®Dye is a trademark of GE Healthcare.
Alexa Fluor® 680, IRDye™ 680RD, CF™ 680 Dye, DyLight® 680
Water, DMF, DMSO