An activated ester for modification of primary amine-containing molecules with DBCO moiety.
DBCO-NHS Ester is an amine-reactive building block used for modification of amine-containing molecules in organic media. It reacts with primary amines (e.g., side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds. Short spacer arm adds minimal mass to modified molecules (228.3 daltons).
This product is not recommended for labelling of proteins or any other biopolymers in aqueous buffers due to poor aqueous solubility.
DMF, DMSO, DCM, TFH, Chloroform
White to slightly grey crystalline