A carboxyl-reactive building block with enhanced stability and water solubility.
The stability of Methyltetrazine-PEG4-Amine is substantially improved compared to hydrogen substituted tetrazines. The aqueous solubility of this reagent is substantially enhanced by a hydrophilic polyethylene glycol (PEG) spacer arm. This reagent is supplied as HCl salt for improved stability and easy handling.
DMF, DMSO, DCM, THF, Chloroform