An azide-activated photo-cleavable biotin probe.
PC Biotin-Azide is an azide-activated photo-cleavable biotin probe that allows for reagent-free release of the captured bio-molecules from streptavidin. This reagent contains a biotin moiety linked to an azide group through a spacer arm containing a photo-cleavable moiety. Captured bio-molecules can be efficiently photo-released, typically >90% in 5-25 minutes using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).
DMF, DMSO, DCM, THF, Chloroform
Yellow amorphous solid to yellow oil