An azide-reactive photocleavable biotin probe
PC Biotin-DBCO is an azide-reactive photocleavable biotin probe that allows for reagent-free release of the captured biomolecules from streptavidin. This reagent contains a biotin moiety linked to DBCO moiety through a spacer arm containing a photocleavable moiety. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).
DMF, DMSO, DCM, THF, Chloroform
Yellow amorphous solid